产品货号：
Z29819
中文名称：
HMMR抗体
英文名称：
Anti-HMMR Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-HMMR Antibody |
| 指标别名 | CD168;HMMR;HMMR-Specific;IHABP;RHAMM |
| 克隆性 | Polyclonal |
| 检验物种 | human |
| 应用范围 | WB,IHC |
| 基因名称 | HMMR |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the C-terminus of human CD168(706-724aa KEGNTNCYRAPMECQESWK). |
| 实际分子量 | 84KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | HMMR,Hyaluronan-mediated motility receptor,is a protein which in humans is encoded by the HMMR gene.RHAMM was originally discovered as a soluble protein that altered migratory cell behavior and bound to hyaluronan,HMMR is less well studied than the main hyaluronan(HA) receptor,CD44.In contrast to CD44 and other cell-surface receptors which contain the classical membrane spanning domain and signal sequence for secretion from the endoplasmic reticulum/Golgi complex,HMMR does not contain a membrane spanning domain nor does the mRNA transcript contain a signal sequence.HMMR normally is localized inside the cell and is only release by certain,poorly defined stimuli.The transport of HMMR to the extracellular space still is unclear but may involve transport channels or proteins,flippase activity,or exocytosis.Intracellularly,HMMR associates with microtubules and,working with BRCA1 and BARD1,plays a role in the regulation of mitosis.Extracellularly,HMMR associates with CD44,and upon binding to HA,activates intracellular signaling pathways.Variants of HMMR caused by alternative splicing have been observed,but not thoroughly studied. |
| Uniprot ID | O75330 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | hyaluronan-mediated motility receptor(RHAMM) |
| 蛋白名全称 | Hyaluronan mediated motility receptor |
| 推荐稀释比 | Western blot(WB) 1:500～2000 Immunohistochemistry(Paraffin-embedded Section) 1:50～400 (Boiling the paraffin sections in 10mM citrate buffer,pH6.0,or PH8.0 EDTA repair liquid for 20 mins is required for the staining of formalin/paraffin sections.) Optimal working dilutions must be determined by end user. |
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